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What is Neuropathic Itch?

Neuropathic itch is an itch that is a result of nervous system damage. This can be a result of direct nerve damage or secondary to a variety of systemic diseases. Because neuropathic itch is a result of nerve damage, there is a variety of associated symptoms, such as burning, tingling, and numbness.

What are the symptoms?

Symptoms of neuropathic itch include:
  • Burning or pain
  • Electric shock sensations or tingling
  • Numbness
  • Severe warmth or cold in the areas of itchiness
  • Increase or decrease in skin sensitivity in the areas of itchiness

Common Questions

Is there a cure for neuropathic itch?

There currently is no medication that completely cures neuropathic itch. Current treatment strategies are directed toward alleviating itch severity, reducing scratching behavior, and addressing any underlying causes that may help treat the symptoms of neuropathic itch. For more information on treating neuropathic itch visit our treatment page here.

Where does neuropathic itch come from?

As noted previously, neuropathic itch can be caused by systemic conditions or by conditions specific to peripheral nerves (nerves in the skin or organs). It is important to consider all the various causes before diagnosing neuropathic itch, so that the underlying cause can be diagnosed and treated.

Systemic causes:
  • Stroke
  • Diabetes
  • Vitamin deficiencies
  • Toxin exposure
  • Multiple sclerosis
Peripheral causes:
  • Brachioradial pruritus, a nerve disorder that specifically targets the arms
  • Notalgia paresthetica, caused by trapping of a nerve
  • Post-herpetic neuralgia, caused by the Herpes Zoster (or shingles) virus damaging local nerves

Is neuropathic itch contagious?

Neuropathic itch is not an infectious disease; therefore, it is not contagious and cannot be passed from one person to another.

How is neuropathic itch diagnosed?

Because there are many causes of neuropathic itch, diagnosis may involve a multidisciplinary team of experts, including neurologists and dermatologists. Based on your specific signs and symptoms, these experts may order skin biopsies, nervous system imaging, or other specific testing to evaluate your itch.