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Treating Neuropathic Itch

Neuropathic Itch Medications

There are many medications that can be used to control symptoms of neuropathic itch. A few treatment options physicians may prescribe based on the severity of symptoms and your individual health include:
Nonspecific itch-reducing household products or medications, such as
  • Calamine lotion
  • Camphor, menthol
  • Diphenhydramine (Benadryl)
  • Capsaicin
Treatment of specific systemic disorders:
  • Diabetes medications (insulin, metformin, SGLT-2 inhibitors, DPP-4 inhibitors) to stabilize blood sugar levels
  • Multiple sclerosis medications (interferon, corticosteroids) to treat long-term and treat flare-ups
Neurologic medications to reduce itch
  • Lidocaine
  • Amitriptyline
  • Pregabalin and gabapentin
  • Naltrexone
Botulinum injections (Botox) can reduce nerve over-activation