There are many medications that can be used to control symptoms of uremic pruritus. A few treatment options physicians may prescribe based on the severity of symptoms and your individual health include:
Nonspecific itch-reducing household products or medications, such as
Moisturizers for dry skin
Camphor, menthol
Diphenhydramine (Benadryl) and other antihistamines
Capsaicin
Medications to reduce factors in the blood that cause itch
Kayexelate for potassium
Cholestyramine for bile acids (made by the liver and secreted by the gallbladder)
Neurologic medications to reduce itch
Pramoxine lotion
Lidocaine
Amitriptyline
Pregabalin and gabapentin
Nalfurafine
Immunosuppressants to reduce inflammation
Dupilumab
Thalidomide
Dialysis can decrease blood levels of electrolytes and other substances that worsen itch by damaging nerves and over-activating the immune system.
